Pros
People are still great, and you're doing important work for patients. Compensation and benefits are competitive-or-better. Nice campus, pleasant place to work.
Cons
Roche management are idiots. The integration virtually destroyed countless departments at this company. Roche was (and is) more interested in protecting their own and showing GNE exactly who's boss than they are in doing the right thing. I saw our department waste 10s of millions of dollars putting in a new database system because the Roche system sucked and they refused to adopt the Genentech system, because it was Genentech (and by definition anything Genentech is bad). I can count two dozen people just from my department who either left or were forced out by idiot management, and all of them were better than the Roche people who replaced them. There's a reason this company has plummeted in the rankings of "best place to work" from #1 a few years ago to about #50, and that free-fall is not going to stop any time soon. Watching this place now is like watching a loved one slowly die. It's agonizing, and I'm glad I moved on before Roche finishes throwing dirt on the body.